A more recent innovation, known as nanoxidil, has begun to steal some of the limelight from other hair loss treatments in the never-ending search for effective solutions to combat hair loss .
As a dermatological problem that affects millions of men around the world, hair loss and hair loss continues to torment the minds, both metaphorically and literally, of a male population that only wants to maintain healthy, full hair for as long as possible.
Therefore, this time we decided to clarify all the doubts about nanoxidil, as an alternative to minoxidil and other topical products for alopecia, to help you in this fight against the dreaded hair loss.
So, what exactly is nanoxidil, and how does it work?
What is nanoxidil?
Nanoxidil is a relatively new molecular chemical compound — compared to topical minoxidil —developed to increase blood flow, promote microcirculation in the scalp , and encourage stimulation of hair follicles , which improves hair density by strengthening hair during its growth phase. In addition, this substance has been shown to possess antioxidant and anti-inflammatory properties that contribute to a healthier hair’s natural environment.
While minoxidil acts as a vasodilator on the scalp, nanoxidil uses a different mechanism of action thanks to nanosomes, microscopic structures or vesicles that encapsulate and transport the active ingredients of a formula. Their tiny composition allows the body to assimilate them more easily and quickly. This system also provides more effective and long-lasting results compared to other hair loss treatment technologies, as, in this particular case, it helps nanoxidil penetrate and act effectively in the deeper layers of the scalp.
What are its benefits, and what is nanoxidil used for?
From the above and as a summary, we can determine that the benefits and uses of nanoxidil for the prevention of baldness and hair loss are:
- Stimulates hair growth. Nanoxidil promotes new hair growth and reactivates hair follicles; with its antioxidant and anti-inflammatory effects, it also protects them from free radical damage and prevents the formation of scar tissue around them, improving scalp health.
- Reduces hair loss. By lengthening the hair growth phase and strengthening hair follicles, while suppressing certain enzymes that cause male pattern baldness, excessive hair loss is significantly reduced.
- Improves hair density and thickness. Since hair stays on the head longer and grows healthily, completing its full cycle, hair acquires a fuller and more voluminous appearance.
Of course, you should remember that the results of nanoxidil may vary from person to person.
Nanoxidil vs. Minoxidil: Similarities and Differences
Both nanoxidil and minoxidil are chemical compounds used as topical treatments to combat hair thinning and loss, and both share the same goal: to stimulate hair growth.
While both are applied to the scalp, nanoxidil uses nanotechnology so its smaller molecules penetrate the skin more easily. This mechanism of action and its lower molecular mass are what differentiate it from minoxidil; thus, some studies suggest that nanoxidil is more effective due to its penetrating power, which improves the efficacy and longevity of the active ingredients in its formula. “The encapsulation of active ingredients in nanosomes promotes uninterrupted hair regeneration for more than 12 hours, a longer duration than conventional hair loss treatments [due to breakage],” DS Labs notes on its website.
Another difference, which is perhaps the main advantage of nanoxidil, is that, according to research so far, it has fewer side effects than minoxidil. This is because the latter requires an alcohol-based excipient to work properly, resulting in possible scalp irritation, while nanoxidil can be made with a propylene glycol-free water-based formula to counteract these adverse reactions.
However, scientific research on nanoxidil is still scarce because it’s a newer hair treatment. The few studies available are limited to tests on women using a specific product called Spectral. DNC-N: “There was a statistically significant decrease in hair loss and a corresponding increase in hair mass index in the third month [of use], which was maintained through the sixth month… The majority of patients—75%—showed an increase in total hair density .” While this doesn’t diminish nanoxidil’s merits, this is where minoxidil stands out, with more extensive medical reviews supporting its effectiveness.
Nanoxidil and minoxidil are often compared, but they are actually different solutions that have similar results in delaying or slowing hair loss and promoting hair density . Keep in mind: The benefits of each one will vary from person to person .
Side effects of nanoxidil
As we mentioned, thanks to its formulation and molecular structure, nanoxidil is usually better tolerated than other hair loss treatments , making it an excellent alternative if you are hypersensitive to the active ingredients in other products.
However, in some very rare cases, you may experience irritation, redness, or itching of your scalp. If this happens, you should see a dermatologist.
Also, during the first few weeks, the ” shedding ” effect may occur, where you’ll notice that your hair is falling out even more than before starting treatment. This is normal and will resolve on its own.
Presentations and how to use nanoxidil
Nanoxidil , as recommended by manufacturers, dermatologists and trichologists, is a topical treatment for hair loss , and is massaged twice a day directly to the affected area and onto dry scalp, to allow the product to be properly absorbed.
Although it’s available over-the-counter in various forms, the most popular being the serum, certified hair care specialists should determine the dosage you need for your specific case. The most popular commercially available format is DS Labs’ Spectral DNC.
Who can use Nanoxidil?
It is important to remember that the use of nanoxidil is prescribed to prevent and delay excessive hair loss and improve hair density , especially in people under forty years of age, who are the ones who can stop the irreversible process of baldness .
As with minoxidil and other hair loss treatments, timing is a determining factor: the sooner you start, the better, and always after a diagnosis from a medical professional. However, as with other similar topical products, nanoxidil does not work as a preventative measure for very advanced cases of androgenetic alopecia —the most common type in men—or alopecia areata, when hair falls out in a patchy pattern in different areas of the head.
Specifically, nanoxidil is recommended for men and women with thinning and hair loss problems due to breakage or derived from male pattern baldness (in its early stages), for those who have reactions or hypersensitivity to other more irritating topical treatments (such as minoxidil), and even for people with hair transplants (because it strengthens the transplanted follicles and the growth of new hair).
Pregnant women should consult a doctor about whether they can use it or not.
How long does it take for nanoxidil to take effect?
As with most hair loss treatments, consistency is key to ensuring nanoxidil is effective and truly achieving optimal results.
The approximate time to notice a clear difference from the first application will be at least three to four months, depending on the individual, if you maintain a daily routine and don’t interrupt use for long periods. This initial period is crucial to truly benefit from the effects of nanoxidil on your hair. Think of it this way: it’s like starting to go to the gym and after two weeks you want to have Henry Cavill’s body in Superman; it’s not impossible, but it doesn’t happen overnight.
Does nanoxidil cause more hair loss?
The answer is yes, but only temporarily. As with minoxidil, there is a period at the beginning of treatment with minoxidil when hair loss increases, known as telogen effluvium or ” shedding .” This phenomenon is normal during the first few weeks of use and is part of the hair renewal process. It usually resolves on its own.
What happens if I stop using nanoxidil?
If you stop using nanoxidil, hair loss is likely to resume, and you will gradually lose the benefits you’ve gained, including the new hair growth you’ve started to see. It’s not recommended to stop using it unless directed by a dermatologist.
In conclusion, as you can see, nanoxidil is a promising alternative for men who want to combat hair loss by improving the thickness, growth, and overall health of their hair and scalp, with fewer side effects compared to minoxidil. However, you should consult a specialist before starting to use it to determine if it’s the best option for you and, above all, remember that results will vary from person to person.
Study cited in this article:
- Effects of a New Topical Treatment Containing Several Hair Growth Promoters in Women with Early Female Pattern Hair Loss.