The hype surrounding Ozempic as a “weight-loss injection” hides serious risks. Without professional guidance, semaglutide can cause adverse effects ranging from vomiting and diarrhea to heart and psychological problems.
Ozempic (semaglutide) has become a global phenomenon beyond its original purpose: the treatment of type 2 diabetes. However, specialists warn that its use as a weight-loss injection without medical supervision can lead to serious complications.
Bariatric surgeon José Antonio Castañeda explained that semaglutide is an effective tool in certain contexts, but it should not be seen as a “magic bullet” for weight loss.
“It is not without serious consequences if not used under strict medical supervision and with a clear understanding of its implications,” he noted in an interview.
Why did Ozempic become popular?
The drug works by stimulating the pancreas to release insulin when blood sugar is high and, by mimicking the hormone GLP-1, regulates how the body converts food into energy. This mechanism decreases appetite, creates a feeling of satiety, and delays gastric emptying, which promotes weight loss.
These characteristics have driven its widespread use among people without diabetes, fueled by viral social media trends. However, specialists describe this phenomenon as “irrational use” that carries significant risks.
Side effects and complications
According to Castañeda and medical sources such as MedlinePlus, the most common adverse effects of semaglutide include:
- Nausea
- Vomiting
- Diarrhea
- Constipation
- Stomachache
- Reflux and heartburn
- Headache
While most are temporary, they can last for weeks. There are also more serious complications that require immediate medical attention, such as pancreatitis, gallstones, heart problems, and a possible increased risk of thyroid tumors.
Impact on mental health
The use of Ozempic has also been linked to psychological disturbances. Dr. Castañeda warns that it can worsen depression and anxiety in some patients. MedlinePlus adds that suicidal thoughts and behavioral changes have been reported. A study published in the Journal of International Medical Research even documented a suicide attempt linked to semaglutide, with improvement after discontinuing treatment.
“Ninety percent of people with obesity make emotional decisions, which makes them vulnerable to quick and dangerous solutions,” warned the specialist, who emphasized the need for psychological stability during obesity treatment.
What does science say about Ozempic for weight loss?
According to the U.S. Food and Drug Administration (FDA), semaglutide does not guarantee sustained weight control when used as a sole supplement to diet and exercise for less than 20 weeks. Furthermore, after discontinuing the medication, most patients regain much of the lost weight.
A comprehensive approach to obesity
Castañeda insists that obesity is a complex disease that cannot be solved with “miracle injections.” Safe and effective treatment requires:
- Lifestyle changes, including a personalized low-calorie diet and at least 150 minutes of aerobic exercise per week.
- Multidisciplinary medical support, with specialists in nutrition, psychology, and bariatric surgery when necessary.
- Access to reliable information that helps prevent self-medication and misinformation on the internet.
“Obesity is a multifactorial problem and requires a comprehensive approach. The quick fixes circulating on social media don’t work and, in many cases, result in surgical complications,” he concluded.